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CRS Abstract Guide
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Session: Technical Session I

Manufacturing Science and Technology

Tuesday, July 9, 2024
9:00 AM – 11:00 AM CET
Location: Sala Italia
Title: Micromixer design: effect of step height, channel cross-sectional shape, and channel geometry on nanoparticle descriptors

Description: Microfluidic-based nanomanufacturing is based on controlling flow and mixing of fluids inside ‘chips’ with channels sized hundreds of microns (1). 3D printing of these ‘chips’ allows the detailed and reproducible customization of the microchannels (2). In this work, we studied the influence of microchannel surface morphology, tunable through 3D printing, on critical particle descriptors, such as size, size distribution, and composition.
Impact: We address "fouling", i.e. the deposition and consequent loss of material onto the channel walls when producing nanoparticles in microfluidic processes. We show that this phenomenon depends on the internal channel morphology and can be prevented through a fluidodynamic-informed design of microfluidic chips.