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Workshop: Recent Advances in the Use of Phospholipid Excipients

Monday, July 8, 2024
8:00 AM – 12:00 PM CET
Location: Magenta A

Sponsored By 
The goals of the workshop are to inform on the basic properties of phospholipid excipients, including physical chemistry aspects, and their use in pharmaceutical technology. Target group are interested academic researchers as well as pharmaceutical industrial scientists interested in the use of phospholipid excipients. The audience will be informed on selection and use of phospholipids in obtaining optimal liposomal dosage forms for various applications, including parenteral depot formulations and hot-melt extrusion for oral formulations of poorly soluble drugs, and on the latest advances on phospholipids in gene replacement therapy, infectious diseases, targeted therapy, nanobubble ablation in ophthalmology.
First Session 

Phospholipids as Excipients (100 min)


  • Chair: Simon Drescher, PD Dr., PRC Heidelberg, Germany


The Phospholipid Research Center Heidelberg: An introduction and ongoing research projects (15 min)


  • Simon Drescher, PD Dr., PRC Heidelberg, Germany


An Introduction on the Use and Properties of Phospholipid Excipients (25 min)


  • Peter van Hoogevest, PhD, University Basel, Switzerland


Phospholipids as Excipients in (Amorphous) Solid Dispersions (25 min)


  • Paulina Skupin-Mrugalska, PhD, Poznan University of Medical Sciences, Poland


Phospholipids in parenteral depot formulations: recent advances, current challenges, and future opportunities (25 min)


  • Paola Luciani, PhD, University Bern, Switzerland 


Q&A (10 min)

Break (30 min) 

Second Session 

Liposomes and LNPs (110 min)


  • Chair: Paola Luciani, PhD, University Bern, Switzerland


Radiocontrolled Drug Delivery with High-Z Elementfunctionalized liposomes (25 min)


  • Mans Broekgaarden, PhD, University Grenoble, France


Phospholipid Nanoparticles for Lipase Deficiency Gene Replacement Therapy (25 min)


  • Davide Brambilla, PhD, University Montréal, Canada


Advancing the Treatment of Infectious Diseases the Key role of Liposomes as Delivery Systems (25 min)


  • Manuela Gaspar, PhD, University of Lisbon, Portugal


Photo-Induced Destruction of Vitreous Opacities Using Nanobubbles Generating Liposomes (25 min)


  • Félix Sauvage, PharmD, PhD, Ghent University, Belgium

Learning Objectives:

At the completion of this activity, participants will know
  • To demonstrate the correlation between the physicochemical properties of the used phospholipids and phospholipid-based dosage forms and the performance of the drug substance (toxicity, efficacy, bioavailability and pharmacokinetics) with mentioned delivery systems.
  • The audience will be informed on the latest advances in this phospholipid area in two sessions: The first session is a more general session on the use of phospholipids as excipients, whereas the second session will focus on application examples from liposomes and lipid nanoparticles (LNPs).